Andreas Wree Selected Research

Type C Niemann-Pick Disease (Niemann Pick Disease, Type C)

3/2021	Gender-Specific Effects of Two Treatment Strategies in a Mouse Model of Niemann-Pick Disease Type C1.
9/2019	Current Challenges in Understanding the Cellular and Molecular Mechanisms in Niemann-Pick Disease Type C1.
6/2019	A therapy with miglustat, 2-hydroxypropyl-ß-cyclodextrin and allopregnanolone restores splenic cholesterol homeostasis in Niemann-pick disease type C1.
3/2018	Evaluation of Two Liver Treatment Strategies in a Mouse Model of Niemann-Pick-Disease Type C1.
4/2017	Increased Regenerative Capacity of the Olfactory Epithelium in Niemann-Pick Disease Type C1.
1/2013	Olfactory deficits in Niemann-Pick type C1 (NPC1) disease.
7/2011	Morphological alterations of the cornea in the mouse model of niemann-pick disease type c1.
1/2011	Corneal alterations during combined therapy with cyclodextrin/allopregnanolone and miglustat in a knock-out mouse model of NPC1 disease.

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Andreas Wree Research Topics

Disease

16	Parkinson Disease (Parkinson's Disease) 01/2022 - 07/2004
8	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 03/2021 - 01/2011
7	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2014 - 01/2003
5	Glaucoma 01/2018 - 07/2012
4	Inflammation (Inflammations) 06/2019 - 01/2013
3	Gliosis 01/2018 - 04/2004
3	Fibrosis (Cirrhosis) 01/2017 - 07/2012
3	Infections 12/2014 - 11/2007
2	Multiple Sclerosis 01/2022 - 12/2006
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2022 - 12/2006
2	Wounds and Injuries (Trauma) 10/2021 - 12/2011
2	Neoplasms (Cancer) 10/2021 - 06/2020
2	Reperfusion Injury 05/2018 - 01/2013
2	Hypoxia (Hypoxemia) 07/2017 - 12/2010
2	Ganglion Cysts (Ganglion) 11/2014 - 08/2010
2	Keratoconus 06/2011 - 02/2011
2	Huntington Disease (Huntington's Disease) 04/2004 - 01/2003
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2022
1	Weight Loss (Weight Reduction) 02/2020
1	Cardiac Arrhythmias (Arrythmia) 01/2020
1	Cardiomyopathies (Cardiomyopathy) 01/2019
1	Paralysis (Palsy) 05/2018
1	Retrograde Degeneration 05/2018
1	Liver Diseases (Liver Disease) 03/2018
1	Niemann-Pick Diseases (Niemann Pick Disease) 01/2018
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2017
1	Body Weight (Weight, Body) 11/2016
1	Central Nervous System Diseases (CNS Diseases) 01/2016
1	Neuroinflammatory Diseases 01/2016
1	Open-Angle Glaucoma (Glaucoma, Open Angle) 09/2015
1	Choroidal Effusions 06/2015
1	Retinal Degeneration 11/2014
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 11/2014
1	Starvation 08/2014
1	Melanoma (Melanoma, Malignant) 06/2013
1	Heart Arrest (Cardiac Arrest) 01/2013
1	Neuralgia (Stump Neuralgia) 01/2013
1	Pain (Aches) 01/2013
1	Cognitive Dysfunction 09/2012
1	Cicatrix (Scar) 07/2012
1	Dementia (Dementias) 10/2011
1	Nausea 10/2011
1	Alzheimer Disease (Alzheimer's Disease) 10/2011
1	Vomiting 10/2011

Drug/Important Bio-Agent (IBA)

9	Oxidopamine (6 Hydroxydopamine)IBA 01/2022 - 12/2008
6	Type A Botulinum Toxins (Botox)FDA Link 01/2022 - 06/2013
6	LipidsIBA 09/2019 - 01/2013
5	Cholinergic Agents (Cholinergics)IBA 01/2020 - 02/2011
5	incobotulinumtoxinA FDA Link 05/2018 - 02/2011
4	CholesterolIBA 06/2019 - 01/2011
4	Pharmaceutical PreparationsIBA 01/2019 - 10/2011
3	miglustat (Zavesca)FDA Link 03/2021 - 11/2016
3	CollagenIBA 07/2012 - 06/2011
3	Peptides (Polypeptides)IBA 10/2011 - 12/2006
2	Botulinum Toxins (Botulinum Toxin)IBA 10/2021 - 02/2011
2	Pregnanolone (Allopregnanolone)IBA 03/2021 - 06/2019
2	Dopamine (Intropin)FDA LinkGeneric 01/2020 - 01/2016
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 07/2012
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 07/2017 - 08/2014
2	CytokinesIBA 01/2017 - 04/2016
2	Ciliary Neurotrophic Factor (CNTF)IBA 04/2004 - 01/2003
1	CuprizoneIBA 01/2022
1	NeurosteroidsIBA 03/2021
1	OligosaccharidesIBA 03/2021
1	Antidepressive Agents (Antidepressants)IBA 01/2021
1	AcetoneIBA 05/2018
1	pentaneIBA 05/2018
1	2-Propanol (Isopropyl Alcohol)FDA LinkGeneric 05/2018
1	HexanesIBA 05/2018
1	pirfenidoneIBA 01/2017
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2016
1	PolymersIBA 09/2015
1	GlycolipidsIBA 11/2014
1	LipofuscinIBA 11/2014
1	tau Proteins (tau Protein)IBA 07/2014
1	Protein Kinases (Protein Kinase)IBA 07/2014
1	RutheniumIBA 06/2013
1	Glial Fibrillary Acidic ProteinIBA 06/2013
1	AntibodiesIBA 01/2013
1	Messenger RNA (mRNA)IBA 01/2013
1	Toll-Like Receptor 2IBA 01/2013
1	salicylhydroxamic acid (SHAM)IBA 01/2013
1	CaspasesIBA 01/2013
1	Thiethylperazine (Thiethylperazine Malate)FDA Link 10/2011
1	Amyloid (Amyloid Fibrils)IBA 10/2011
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 10/2011
1	SterolsIBA 07/2011

Therapy/Procedure

10	Therapeutics 03/2021 - 01/2011
7	Injections 01/2022 - 12/2008
2	Lasers (Laser) 12/2011 - 07/2006
2	Transplantation 12/2006 - 09/2004
1	Subcutaneous Injections 06/2020
1	Euthanasia (Mercy Killing) 02/2020
1	Laparotomy 05/2018
1	Refractive Surgical Procedures 12/2014
1	Brachytherapy 06/2013
1	Ligation 01/2013
1	Cardiopulmonary Resuscitation (CPR) 01/2013
1	Glaucoma Drainage Implants 01/2013
1	Trabeculectomy (Trabeculoplasty) 07/2012